Wellness Wednesday: Independently Verified Pregnancy Rates

In 2013, Genesis Fertility Centre became the first and only clinic in Canada to independently verify our clinical results. We did this to improve transparency about our clinic’s pregnancy rates and translate for patients procedural success rates that are often reported in different ways.

In the U.S., reporting of pregnancy rates by fertility clinics is mandatory, audited and identifiable. In Canada, reporting is voluntary, de-identified and unaudited. Websites may contain only biochemical pregnancy rates* and use different denominators, making it virtually impossible for patients to compare the success rates of different fertility clinics.

At Genesis, we ensure validity of our pregnancy rates annually through third-party auditing conducted by two independent, unrelated industry organizations: Fertility Authority, a leading authority in patient advocacy, and IVF Reports, an authority in IVF standards.

At Genesis Fertility Centre, we believe that singleton pregnancies are healthiest for mothers and babies as multiple implantation’s increase the risk of pre-term delivery and obstetrical complications.

Between January 2011 and December 2012, Genesis’s elective and mandatory single embryo transfer rate was 18%.

In 2013, elective day-five single embryo (eSET) utilization increased to 76% for eligible women under age 37 (table 3).

Elective single day-five embryo transfer (eSET) in women under age 37 at Genesis Fertility Centre (independently verified, January 2013 - July 2014).

 

What do these numbers mean?

Pregnancy rates may be reported in several ways due to various definitions of pregnancy (see Table 4). The denominator against which positive pregnancies are measured also vary:

  1. The start of an IVF cycle, i.e. the start of fertility medication
  2. Egg retrieval
  3. Embryo transfer

We report according to fresh embryo transfer.

Independently verified pregnancy rates (%) per fresh embryo transfer for Genesis Fertility Centre (January 2013 - July 2014).

 

Why do we report according to fresh embryo transfer?

Many patients now choose to freeze their embryos for later use rather than proceed with embryo transfer immediately. Also, some patients with poorer prognoses or more challenging histories (e.g. AMH levels of <0.5; multiple previous failed cycles at the same or different fertility clinics) may have poorer progression to transfer, i.e. no embryo to transfer. In the past, these patients may have been denied a chance to try. We take pride in accepting these “challenging cases” provided the patients understand the prognoses. We are honoured to help them build their families.

Not all egg retrievals result in embryo transfer:

  • Fertility preservation for patients with cancer or other medical issues
  •  Cryopreservation of embryos for later use due to:

i. Genetic screening (day-five embryo biopsy and freezing while awaiting results of testing)
ii. Risk of ovarian hyperstimulation
iii. Uterine factor infertility
iv. Other, e.g. personal or health reasons

  • No eggs retrieved (this occurs at a frequency of <1% in a normal responder)
  •  Failed fertilization (occurs in <5% of cases)
  • Failed embryo development (occursin <1% of cases)

We intend to post our pregnancy rates according to age, AMH levels and previous attempts on our website to allow patients to interpret their individual circumstances. Stay tuned!

*Biochemical pregnancy rates are defined as positive blood tests done 17 days after the embryo transfer.

Babies Born Using Donated Wombs

(Photo Credit: gabi_menashe via photopin cc)

It’s been a busy week for fertility science. This past weekend, the world welcomed the first baby born from a transplanted womb and on Monday, it was announced that another two women are set to give birth using their mothers’ wombs.

Why are these developments so important to the fertility field?

There are many causes for infertility, but one of the most challenging causes is Mayer-Rokitansky-Küster-Hauser (MRKH) Syndrome, a congenital defect which occurs in 1 in 4,500 women where they are born without a uterus. This condition, and other conditions such as Asherman’s syndrome (an acquired uterine condition characterized by scar tissue formation inside the uterus and/or the cervix), can benefit from uterus transplants as a potential treatment for infertility. Previously, these conditions have had few to no options for treatment without the involvement of gestational carriers or resorting to adoption.

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Vancouver’s Genesis Fertility Centre celebrates birth of first baby in Canada using the Eeva Test

Genesis Fertility Centre - Logo

NEWS RELEASE

Vancouver, B.C. – September 24, 2014 – The first baby in Canada conceived with the assistance of the Early Embryo Viability Assessment (Eeva®) Test at Vancouver’s Genesis Fertility Centre was born this past August. Olivia, born to Darla Macey-Nicholson and Craig Nicholson, was conceived through in vitro fertilization (IVF) with the help of novel embryo development information provided by the Eeva®Test.

The Eeva® Test, which is exclusively distributed in Canada by EMD Serono, a division of EMD Inc., Canada, is a significant innovation for reproductive technology. The test is a tool which helps embryologists in assessing the embryo most likely to develop for implantation, ultimately aiding fertility experts achieve better outcomes for their patients. Developed by Auxogyn Inc., a company dedicated to advancing women’s reproductive health, the Eeva® Test is based on patented technology developed by StanfordUniversity researchers. This team of university researchers is world-renowned for pioneering techniques in time-lapse imaging of stem cells.

“We are honoured to have helped conceive the first Eeva® baby in Canada,” says Dr. Sonya Kashyap MD, medical director of Genesis Fertility Centre. “It demonstrates that Eeva can act as a tool to improve success rates of IVF in addition to increasing patients’ overall experience to achieve pregnancy. These are our two most important goals.”

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Reduce the Stress of Pregnancy with Restorative Yoga

Reduce the Stress of Pregnancy with Restorative Yoga

 

These days, more and more people are taking up the practice of yoga as a way to keep themselves fit and healthy both physically and mentally.

Yoga itself has long been lauded as bestowing upon its practitioners many direct and indirect health benefits from increased flexibility to reduced blood pressure, but is it safe to practice yoga during pregnancy?

Alan Kemp from Alanfitness.ca in Vancouver is back to share some of his yogic and fitness knowledge with you.

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Wellness Wednesdays: 11 Tips to a Healthier Pregnancy

It’s Wellness Wednesday!

Wellness Wednesdays: 11 Tips to a Healthier Pregnancy

Wellness Wednesdays: 11 Tips to a Healthier Pregnancy

For this week’s post, our medical director, Dr. Sonya Kashyap, has some healthy pregnancy advice for those who have or are trying to conceive.

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Big box

I am not sure the rules around internet postings and corporate rights so I’ll be indirect. Today I was at a large membership-based big box store in downtown Vancouver. I was buying the usual 12 packs of things I don’t need. I walked past the pregnancy tests. The store was selling a four pack of pregnancy tests for about $19. I had to take a second look as I thought surely it must be 40, and not four, for that price. No, it was for four. This is very, very expensive. They are available for far less money on-line.

Now, everyone knows someone who will tell you that the cheap urine pregnancy tests didn’t work, or that no urine pregnancy tests (cheap or expensive) worked to detect their pregnancies but for MOST people MOST of the time the less expensive urine pregnancy tests you can buy on-line will be accurate.

I am not trying to undercut store-front merchants but simply trying to put downward pressure on their prices. When I was buying pregnancy tests I bought them from a Canadian-owned, online retailer. I paid about $1 per test. A quick google tonight confirms that there are several such Canadian retailers charging around that same price today.

Full disclosure: I am not pregnant, I do not need pregnancy test strips for personal use and have no plans to be pregnant again.

I am posting this as a public service announcement: please do not spend big dollars on brand name pregnancy test strips as the less expensive test strips almost always work just as well.

Genesis Fertility Centre
Reproductive Endocrinology & Infertility

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