The recent news that actress Sofia Vergara is facing a lawsuit from her ex-fiancé over the fate of their frozen embryos is shining a light on the embryo freezing process. Dr. Kashyap explores some of the complications surrounding embryo freezing in comparison to egg freezing over on The Huffington Post
Isang taon na naman ang nakalipas at pinagmamalaki kong sabihin na maraming magandang nagaganap dito sa Genesis. Matagumpay ang aming open houses at egg freezing event. Ang pinaka-unang eEva baby ng Genesis ay pinanganak na rin.
Noong nakaraang Oktobre, ako ay nagkaroon ng pagkakataon na makapunta sa ASRM convention sa Hawaii. Para sa akin, ito ay isang magandang karanasan dahil sa mga bagong updates at mga bagong pag-aaral para matulungan ang mga pasyente sa kanilang infertility issues.
Kami po dito sa Genesis ay nagkakaisa sa aming layunin na matulungan ang lahat sa kanilang hangarin na magkaroon ng kumpletong pamilya.
Kami din po ay taos pusong nagpapasalamat sa lahat ng sumuporta at naniniwala sa aming kakayahan. Patuloy po kaming tutulong sa inyo. Maraming salamat at mabuhay tayong lahat.
We are proud of the many positive things that have happened at Genesis over the past year, like our successful open houses and egg freezing event. As well as the birth of the first EEVA baby in Canada achieved through our clinic.
Last October , I had the opportunity to attend the ASRM convention in Hawaii . It was a great experience because I got to learn about new updates and new studies to help patients with their infertility issues.
We here at Genesis are united in our goal to help all of those hoping to complete their family. We are deeply grateful for all of the support from our patients and believe in our abilities to help make their dreams a reality. We look forward to helping you in the year to come. Thank you!
In 2013, Genesis Fertility Centre became the first and only clinic in Canada to independently verify our clinical results. We did this to improve transparency about our clinic’s pregnancy rates and translate for patients procedural success rates that are often reported in different ways.
In the U.S., reporting of pregnancy rates by fertility clinics is mandatory, audited and identifiable. In Canada, reporting is voluntary, de-identified and unaudited. Websites may contain only biochemical pregnancy rates* and use different denominators, making it virtually impossible for patients to compare the success rates of different fertility clinics.
At Genesis, we ensure validity of our pregnancy rates annually through third-party auditing conducted by two independent, unrelated industry organizations: Fertility Authority, a leading authority in patient advocacy, and IVF Reports, an authority in IVF standards.
At Genesis Fertility Centre, we believe that singleton pregnancies are healthiest for mothers and babies as multiple implantation’s increase the risk of pre-term delivery and obstetrical complications.
Between January 2011 and December 2012, Genesis’s elective and mandatory single embryo transfer rate was 18%.
In 2013, elective day-five single embryo (eSET) utilization increased to 76% for eligible women under age 37 (table 3).
What do these numbers mean?
Pregnancy rates may be reported in several ways due to various definitions of pregnancy (see Table 4). The denominator against which positive pregnancies are measured also vary:
- The start of an IVF cycle, i.e. the start of fertility medication
- Egg retrieval
- Embryo transfer
We report according to fresh embryo transfer.
Why do we report according to fresh embryo transfer?
Many patients now choose to freeze their embryos for later use rather than proceed with embryo transfer immediately. Also, some patients with poorer prognoses or more challenging histories (e.g. AMH levels of <0.5; multiple previous failed cycles at the same or different fertility clinics) may have poorer progression to transfer, i.e. no embryo to transfer. In the past, these patients may have been denied a chance to try. We take pride in accepting these “challenging cases” provided the patients understand the prognoses. We are honoured to help them build their families.
Not all egg retrievals result in embryo transfer:
- Fertility preservation for patients with cancer or other medical issues
- Cryopreservation of embryos for later use due to:
i. Genetic screening (day-five embryo biopsy and freezing while awaiting results of testing)
ii. Risk of ovarian hyperstimulation
iii. Uterine factor infertility
iv. Other, e.g. personal or health reasons
- No eggs retrieved (this occurs at a frequency of <1% in a normal responder)
- Failed fertilization (occurs in <5% of cases)
- Failed embryo development (occursin <1% of cases)
We intend to post our pregnancy rates according to age, AMH levels and previous attempts on our website to allow patients to interpret their individual circumstances. Stay tuned!
*Biochemical pregnancy rates are defined as positive blood tests done 17 days after the embryo transfer.
At Genesis, supporting our patients through successful treatment is our top priority. This applies to all the procedures we perform at our centre, including egg freezing.
Egg freezing is a delicate process and its success rates are highly dependent on method and experience. Thanks to our talented and seasoned team we have managed to achieve high success rates (Table 1).
Most women do not return for their frozen eggs for many years, so the number of women who have attempted to become pregnant from these eggs is limited. For this reason, quality assurance in the egg survival process is paramount, and has helped us achieve a thawed egg survival rate of 95%.
An increasing number of women are interested in having children later in life for a variety of reasons:
- Meeting the right life partner
- Focusing on education and career development
- Seeking financial stability prior t o having a child
When a woman is in her late 30s or older, there is a decreased chance of pregnancy and an increased chance of pregnancy loss and chromosomal abnormalities. Women can now choose to freeze their eggs through vitrification at Genesis.
Patients with Cancer
Advances in cancer treatment have increased survival rates over the past decades. However, many cancer treatments can permanently affect fertility for both men and women. In women, cancer treatment may deplete the number of eggs in the ovaries and trigger early menopause. If you will be receiving chemotherapy imminently, your doctor may refer you and you will be seen within 24 to 48 hours to discuss your fertility options.
Fertility can be preserved through the freezing of sperm, eggs and embryos. Our team works closely with oncology teams to ensure any fertility treatment is safe.
Steps to Egg Freezing
Women who elect to freeze their eggs undergo the same initial steps as an IVF treatment cycle. Vitrified eggs are then banked and can be stored for many years. Women are encouraged to access this treatment prior to age 38 to increase the chance of pregnancy when their eggs are thawed, fertilized and transferred at a time in their life when pregnancy is desired. We have observed success of frozen eggs up to age 38 but consider patients on a case by case basis up to 42.
Our medical director Dr. Sonya Kashyap recently penned a detailed article for the Huffington Post entitled “Egg Freezing Deserves Serious Consideration.” The article provides detailed background information on the fertility procedure and how it applies to Canadians.
Здравствуйте! Я – Лариса из Минска, Беларусь. Работаю в нашей клинике с 2010 года, сначала как андролог, затем специализировалась на эмбриологии. Андрологи и эмбриологи работают плечом к плечу. Мне очень приятно сказать, что мои коллеги – действительно увлеченные и замечательные люди.
We were very fortunate to have Paula Schuck of Thrifty Mommas Tips join us at our November egg freezing informational event.
Paula had a chance to blog about the event, her newly acquired knowledge of egg freezing, as well as the inspirational stories of two of our wonderful patients: Anna Kashani and Heather Pelz.
Read about egg freezing as well as Anna and Heather below!
On Tuesday November 4, our clinic hosted an informal egg freezing information event for professional women at Coast Restaurant. The event was created for women to learn about the science behind egg freezing, information that may help them when they make their family planning decisions. In addition, the information session was a unique opportunity for people to discuss reproductive health outside a clinical setting and meet patients who have experienced fertility issues.
Yumi Ang of Hello Vancity was at the event and had a chance to speak with our medical director, Dr. Sonya Kashyap, as well as two patients who were willing to share their struggles with infertility. Here is Yumi’s take on how fertility planning affects professional women.