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Wellness Wednesday: Comprehensive Chromosomal Screening & Preimplantation Genetic Diagnosis

Genesis Fertility Centre is committed to fertility patient care, and screening for chromosomal abnormalities can help reduce the probability of a failed cycle, miscarriage or abnormal pregnancy from an IVF cycle. At our clinic, we offer both comprehensive chromosomal screening (CCS; Table below) and pre-implantation genetic diagnosis (PGD).

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Genesis pregnancy rate for CCS patients of all ages (2014).

What is Comprehensive Chromosomal Screening?

CCS, also known as preimplantation genetic screening (PGS), allows fertility specialists to identify a chromosomally balanced embryo for transfer with 98% certainty. Screening embryos prior to implantation can help achieve higher success rates and fewer pregnancy losses, particularly for women over 35 years old, patients with multiple-failed IVF cycles, implantation failures or repeated miscarriages.

For women under age 35, more of their embryos will be balanced (euploid). Nevertheless, there are some younger patients who prefer CCS. An example would be unexplained recurrent pregnancy loss or previously chromosomally abnormal pregnancies.

Due to age-related infertility, for women over age 38, most of their embryos will be abnormal (aneuploid) and CCS can help reduce the time needed to successfully conceive by avoiding the transfer of an abnormal embryo.

What is pre-implantation genetic diagnosis and how is it different than CCS?

PGD is a test offered to patients who have a high risk of transmitting a known single-gene defect to their child, such as Tay-Sachs disease, haemophilia and cystic fibrosis.

If you would like to speak with one of our nurses about CCS or PGD, please call us at 604.879.3032

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